The tissue structure of Striate+™ Improved bone regeneration Striate+™ collagen membranes feature a bilayer structure with a rough side and a smooth side to stimulate specific biological responses. The rough side, which faces the bone defect, consists of a loose distribution of collagen bundles that forms an open scaffold for the entry of osteogenic cells. The smooth side facing the soft tissue consists of densely packed collagen bundles arranged in parallel, which in their barrier function prevent the migration of the gingival cells into the defect. Striate+™ was developed to protect the bone graft from epithelial cell ingrowth and to create a favorable environment for osteogenesis – with a predictable resorption time for protected bone regeneration. 1 The pore dimension of the smooth surface structure prevents the ingrowth of connective tissue allows angiogenic development of the membrane 2 The rough membrane structure meets the requirements for osteoconductivity allows the migration of cells from the native bone 2 1 Properties of the different surface structures Next to the three-dimensional membrane structure, these concern features to achieve optimal hard and soft tissue conditions: Smooth side with dense collagen structure for barrier function Osteoconductive, rough side with bioactive chambers – serves as a guide for cells and blood vessels
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