SynMax® and PermaPro® – synthetic alternatives SynMax® – osseous integration with following controlled resorption [1, 2] Commonly used bone substitutes are human bone, i.e. autografts or allografts, bone material from other species or synthetic materials. While autografts are considered the “gold standard” with regard to biocompatibility their use is hampered by concomitant donor site pain and morbidity and volume limitations of how much material can be harvested. Therefore, considerable efforts are made to investigate the use of materials from alternative sources and to develop techniques that do not rely on harvesting autogenous bone but do in result in sufficient bone formation within a short time frame. SynMax® is a fully synthetic, safe and biocompatible material that, when brought into an osseous environment, serves as an osteoconductive scaffold to support the ingrowth and fusion of adjacent, vital bone. SynMax® is composed of 60 % hydroxyapatite and 40 % beta-tricalcium phosphate. After implantation, the material undergoes a natural remodeling and is gradually resorbed and replaced by new bone. PermaPro® – high-density PTFE barrier membrane PermaPro® is an exceptionally thin, non-resorbable, biologically inert and biocompatible membrane made of high-density polytetrafluoroethylene (PTFE). PermaPro® maintains its structural characteristics both during the initial implantation and over the whole healing time. Due to its dense structure, the membrane acts as an efficient barrier against bacterial and cellular penetration, and may therefore be left in place for open healing in certain indications. The use of PermaPro® is especially recommended for regeneration of bone defects outside the ridge contour because it offers a higher stability and superior space-maintaining properties compared to resorbable (collagen) membranes. In addition, open healing with PermaPro® in socket or ridge preservation enables maintenance of the soft tissue architecture and contours since no primary wound closure is required. Due to the missing flap closure, the mucogingival line will not be displaced and the attached/keratinized gingiva will be preserved.
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